Uterine Fibroid Embolisation References

RAMDOMISED TRIALS:

Scottish REST trial comparing UAE with surgery: In this randomized trial comparing uterine-artery embolization with standard surgical treatment for women with symptomatic fibroids, we found no significant differences between the groups in measures of quality of life at 12 months” “Uterine-artery embolization was associated with a significantly faster recovery, including the resumption of usual activities.” View link

Scottish REST trial comparing UAE with surgery: In this randomized trial comparing uterine-artery embolization with standard surgical treatment for women with symptomatic fibroids, we found no significant differences between the groups in measures of quality of life at 12 months” “Uterine-artery embolization was associated with a significantly faster recovery, including the resumption of usual activities.” View link

Dutch EMMY trial comparing UAE with Hysterectomy: “This large, randomized, long-term follow-up trial demonstrates that UAE is a good alternative to hysterectomy for the treatment of menorrhagia caused by uterine fibroids.” View link

Large UK based Multicentre cohort study. Results of the HOPEFUL trial comparing Uterine Artery Embolization (UAE) with Hysterectomy. “The evidence that we have accumulated strongly suggests that UAE is a safe procedure over the medium term, with fewer significant complications than hysterectomy, and has an important role in the effective treatment of symptomatic fibroids.” View link

A select References list for more relevant papers on UFE. View link

UK Fibroid Registry View link

A Cochrane Review. Uterine Artery Embolization for symptomatic uterine fibroids. Gupta et al. Published 26.12.2014 View link

The latest Guidelines from NICE published in Nov 2010 state;- ”Current evidence on uterine artery embolisation (UAE) for fibroids shows that the procedure is efficacious for symptom relief in the short and medium term for a substantial proportion of patients. There are no major safety concerns.” and link behind the word ‘NICE’ to this page which gives these guidelines in full. View link